产品概述：Purified recombinant protein of Human major histocompatibility complex, class II, DR beta 5 (HLA-DRB5), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding human full-length HLA-DRB5

表达系统：E. coli

种属：Human

标签类型：N-GST and C-His

分子量：55 kDa

通用名：HLA-DRB5

总结：HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. There are multiple pseudogenes of this gene. [provided by RefSeq, Feb 2020]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris, pH8.0, 8M Urea.

别名：HLA-DRB5*