ADRA2C polyclonal antibody
产品名称： ADRA2C polyclonal antibody
英文名称： ADRA2C polyclonal antibody
产品编号： PAB25565
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ADRA2C.
- Immunogen:
- A synthetic peptide corresponding to 18 amino acids at 3rd cytoplasmic domain of human ADRA2C.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Form:
- Liquid
- Purification:
- Immunoaffinity chromatography
- Storage Buffer:
- In PBS (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (12 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 152
- Gene Name:
- ADRA2C
- Gene Alias:
- ADRA2L2,ADRA2RL2,ADRARL2,ALPHA2CAR
- Gene Description:
- adrenergic, alpha-2C-, receptor
- Omim ID:
- 104250
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq
- Other Designations:
- alpha-2C-adrenergic receptor,alpha2-AR-C4
- Gene Pathway
- Related Disease
- Acute Disease
- Attention Deficit Disorder with Hyperactivity
- Cardiomyopathy, Dilated
- Cognition
- Cognition Disorders
- Death, Sudden, Cardiac
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Disease Progression
- Dyspepsia
- Genetic Predisposition to Disease
- Heart Failure, Congestive
- Hypertension
- Hypotension, Orthostatic
- Irritable Bowel Syndrome
- Long QT Syndrome
- Long QT syndrome
- Low Back Pain